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PUBMED (ONLINE) RESOURCES, RESEARCH STUDIES PG. 2

The Role of Laser Biostimulation in Early Post-Surgery Rehabilitation

Effects of Laser Therapy on Pain and Scar Formation after Inguinal Herniation Surgery

Effects of Laser Therapy on Pain and Scar Formation after Inguinal Herniation Surgery

http://www.ncbi.nlm.nih.gov/pubmed/20203347 


OBJECTIVE: Low energy infrared laser radiation had a beneficial effect on the covering of the scar with stratified squamous cornifying epithelium and intensified wound healing.   


CONCLUSION:  The gross and microscopic findings indicated a beneficial effect of laser stimulation on wound healing. These results underscore the utility of biostimulation lasers in the early post-operative period. Physio-mechanical investigations did not reveal an effect of infrared laser biostimulation on the breaking strength of the cutaneous scar.  

Effects of Laser Therapy on Pain and Scar Formation after Inguinal Herniation Surgery

Effects of Laser Therapy on Pain and Scar Formation after Inguinal Herniation Surgery

Effects of Laser Therapy on Pain and Scar Formation after Inguinal Herniation Surgery

http://www.ncbi.nlm.nih.gov/pubmed/19821701?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=62 


OBJECTIVE:  The aim of this study was to investigate the efficacy of an infrared GaAlAs laser operating with a wavelength of 830 nm in the postsurgical scarring process after inguinal-hernia surgery.  


CONCLUSION:  Infra-red photomedicine therapy (830 nm) applied after inguinal-hernia surgery was effective in preventing the formation of keloids. In addition, photomedicine therapy resulted in better scar appearance and quality 6-month post surgery.  

Low-Level Laser Therapy for Implants Without Initial Stability

Effects of Laser Therapy on Pain and Scar Formation after Inguinal Herniation Surgery

The Efficacy of Laser Therapy in Wound Repair: a Meta-Analysis of the Literature

http://www.ncbi.nlm.nih.gov/pubmed/19860572?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=48 


OBJECTIVE: This study evaluated the effect of low-level infrared laser on removal torque values of implants with poor initial stability inserted in rabbit tibias.  


CONCLUSION:  In this study, low-level laser therapy promoted the osseointegration of implants with poor initial stability, particularly in the initial stages of bone healing.

The Efficacy of Laser Therapy in Wound Repair: a Meta-Analysis of the Literature

The Efficacy of Laser Therapy in Wound Repair: a Meta-Analysis of the Literature

The Efficacy of Laser Therapy in Wound Repair: a Meta-Analysis of the Literature

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=OBJECTIVE&list_uids=15315732&query_hl=10&itool=pubmed_DocSum 


OBJECTIVE: We determined the overall effects of laser therapy on tissue healing by aggregating the literature and subjecting studies meeting the inclusion and exclusion criteria to statistical meta-analysis.  


CONCLUSION:  We conclude that laser therapy is an effective tool for promoting wound repair 

A Meta-Analysis of the Efficacy of Laser Phototherapy on Pain Relief

The Efficacy of Laser Therapy in Wound Repair: a Meta-Analysis of the Literature

A Meta-Analysis of the Efficacy of Laser Phototherapy on Pain Relief

https://www.ncbi.nlm.nih.gov/pubmed/20842007


OBJECTIVE: Laser phototherapy has been widely used to relieve pain for more than 30 years, but its efficacy remains controversial. To ascertain the overall effect of phototherapy on pain, we aggregated the literature and subjected the studies to statistical meta-analysis.  


CONCLUSION: These findings warrant the conclusion that laser phototherapy effectively relieves pain of various etiologies; making it a valuable addition to contemporary pain management armamentarium. 


Laser Therapy Efficacy in Post-Operative Wounds

The Efficacy of Laser Therapy in Wound Repair: a Meta-Analysis of the Literature

A Meta-Analysis of the Efficacy of Laser Phototherapy on Pain Relief

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=OBJECTIVE&list_uids=15782037&query_hl=10&itool=pubmed_docsum 


OBJECTIVE: The aim of this paper was to investigate the efficacy of low-level laser radiation (LLLR) with wavelength of 904 nm on the stimulation of the healing process of postoperative aseptic wounds (early scar).  


CONCLUSION:  LLLR with wavelength of 904 nm to stimulate postoperative aseptic wounds (early scar) is efficient in both cases of cutting plague 


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Laser Therapy as an Effective Therapeutic Modality for Delayed Wound Healing

Efficacy of Laser Therapy in Reducing Postoperative Pain After Endodontic Surgery

Efficacy of Laser Therapy in Reducing Postoperative Pain After Endodontic Surgery

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=OBJECTIVE&list_uids=16387711&query_hl=18&itool=pubmed_DocSum 


OBJECTIVE: Laser therapy  is a form of phototherapy that involves the application of low power monochromatic and coherent light to injuries and lesions. It has been used successfully to induce wound healing in nonhealing defects. Other wounds treated with lasers include burns, amputation injuries, skin grafts, infected wounds, and trapping injuries. The unique properties of lasers create an enormous potential for specific therapy of skin diseases.   


CONCLUSION:  As with any new device, the most efficacious and appropriate use requires an understanding of the mechanisms of light interaction with tissue as well as the properties of the laser itself. 

Efficacy of Laser Therapy in Reducing Postoperative Pain After Endodontic Surgery

Efficacy of Laser Therapy in Reducing Postoperative Pain After Endodontic Surgery

Efficacy of Laser Therapy in Reducing Postoperative Pain After Endodontic Surgery

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=OBJECTIVE&list_uids=14758818&query_hl=18&itool=pubmed_DocSum 


OBJECTIVE: The aim of the study was to evaluate the effect of low level laser application on postoperative pain after endodontic surgery in a double blind, randomized clinical study.


CONCLUSION:  Low level laser therapy can be beneficial for the reduction of postoperative pain.  


Effect of Laser Therapy Treatment on Neurosensory Deficits

Efficacy of Laser Therapy in Reducing Postoperative Pain After Endodontic Surgery

Increased Fibroblast Proliferation Induced by LED and Laser Irradiation

http://www.ncbi.nlm.nih.gov/pubmed/8863301?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum 


OBJECTIVE: Laser treatment has been advocated as a possible treatment for patients with paresthesia. An objectively verified improvement in sensory function is relevant if, at the same time, it is perceived as a subjective improvement by the patient. The aim of this double blind clinical study was to see if low-level laser treatment with a GaAlAs laser (820 nm, Rønvig, Denmark) resulted in objectively verified improvement in sensory function and whether this correlated with the patient's subjective evaluation subsequent to treatment.


CONCLUSION:  In conclusion GaAlAs laser therapy treatment results in both a subjective and objective improvement in mechanical sensory perception in long-standing neurosensory deficit in the inferior alveolar nerve.  

Increased Fibroblast Proliferation Induced by LED and Laser Irradiation

Wound Healing of Animal and Human Body Sport and Traffic Accident Injuries Using Laser Therapy

Increased Fibroblast Proliferation Induced by LED and Laser Irradiation

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=OBJECTIVE&list_uids=12928819&query_hl=18&itool=pubmed_DocSum 


OBJECTIVE: As Light Emitting Diode (LED) devices are commercially introduced as an alternative for Low Level Laser (LLL) Therapy, the ability of LED in influencing wound healing processes at cellular level was examined.


CONCLUSION:  LED and laser therapy irradiation resulted in an increased fibroblast proliferation in vitro. This study therefore postulates possible stimulatory effects on wound healing in vivo at the applied dosimetric parameters.  





Wound Healing of Animal and Human Body Sport and Traffic Accident Injuries Using Laser Therapy

Wound Healing of Animal and Human Body Sport and Traffic Accident Injuries Using Laser Therapy

Wound Healing of Animal and Human Body Sport and Traffic Accident Injuries Using Laser Therapy

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=OBJECTIVE&list_uids=11800105&query_hl=10&itool=pubmed_DocSum 


OBJECTIVE: The main objective of current animal and clinical studies was to assess the efficacy of laser therapy on wound healing in rabbits and humans.


CONCLUSION:  In addition to accelerated wound healing, the main advantages of LASER THERAPY for postoperative sport- and traffic-related injuries include prevention of side effects of drugs, significantly accelerated functional recovery, earlier return to work, training and sport competition compared to the control group of patients, and cost benefit.  

A Randomized, Placebo Controlled Trial of Laser Therapy for Activated Achilles Tendonitis...

Wound Healing of Animal and Human Body Sport and Traffic Accident Injuries Using Laser Therapy

Wound Healing of Animal and Human Body Sport and Traffic Accident Injuries Using Laser Therapy

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=OBJECTIVE&list_uids=16371497&query_hl=29&itool=pubmed_docsum


OBJECTIVE: To investigate in situ if laser therapy has an anti-inflammatory effect on activated tendinitis of the human Achilles tendon.


CONCLUSION:  LASER THERAPY at a dose of 5.4 J per point can reduce inflammation and pain in activated Achilles tendonitis. LASER THERAPY may therefore have potential in the management of diseases with an inflammatory component.   

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Laser therapy treatment of tendinopathy: A Systematic Review with Meta-analysis

Laser Therapy Facilitates Superficial Wound Healing in Humans: A Triple-Blind, Sham-Controlled Study

Laser Therapy Facilitates Superficial Wound Healing in Humans: A Triple-Blind, Sham-Controlled Study

http://www.ncbi.nlm.nih.gov/pubmed/19708800?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=90 


OBJECTIVE: To assess the clinical effectiveness of Low Level Laser Therapy (LLLT) in the treatment of tendinopathy. Secondary objectives were to determine the relevance of irradiation parameters to outcomes, and the validity of current dosage recommendations for the treatment of tendinopathy.

 

CONCLUSION:  LASER THERAPY can potentially be effective in treating tendinopathy when recommended dosages are used. The 12 positive studies provide strong evidence that positive outcomes are associated with the use of current dosage recommendations for the treatment of tendinopathy.  

Laser Therapy Facilitates Superficial Wound Healing in Humans: A Triple-Blind, Sham-Controlled Study

Laser Therapy Facilitates Superficial Wound Healing in Humans: A Triple-Blind, Sham-Controlled Study

Laser Therapy Facilitates Superficial Wound Healing in Humans: A Triple-Blind, Sham-Controlled Study

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=OBJECTIVE&list_uids=15496990&query_hl=39&itool=pubmed_docsum 


OBJECTIVE:  Low-level laser therapy (LLLT) has been promoted for its beneficial effects on tissue healing and pain relief. However, according to the results of in vivo studies, the effectiveness of this modality varies. Our purpose was to assess the putative effects of LLLT on healing using an experimental wound model. 


CONCLUSIONS:  LASER THERAPY resulted in enhanced healing as measured by wound contraction. The untreated wounds in subjects treated with LASER THERAPY contracted more than the wounds in the sham group, so LASER THERAPY may produce an indirect healing effect on surrounding tissues. These data indicate that LASER THERAPY is an effective modality to facilitate wound contraction of partial-thickness wounds.

Effect of NASA Light-Emitting Diode Irradiation on Wound Healing

Laser Therapy Facilitates Superficial Wound Healing in Humans: A Triple-Blind, Sham-Controlled Study

Effect of NASA Light-Emitting Diode Irradiation on Wound Healing

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=OBJECTIVE&list_uids=11776448&query_hl=7&itool=pubmed_docsum 


OBJECTIVE: The purpose of this study was to assess the effects of hyperbaric oxygen (HBO) and near-infrared light therapy on wound healing.


CONCLUSION:  We believe that the use of NASA LED for light therapy alone, and in conjunction with hyperbaric oxygen, will greatly enhance the natural wound healing process, and more quickly return the patient to a preinjury/illness level of activity. This work is supported and managed through the NASA Marshall Space Flight Center-SBIR Program.  



Carpal Tunnel Syndrome Pain Treated with Laser and Electric

The Effects of Laser Therapy in Clinical Outcome and Neurophysiological Results of Carpal Tunnel...

Effect of NASA Light-Emitting Diode Irradiation on Wound Healing

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=OBJECTIVE&list_uids=12098159&query_hl=29&itool=pubmed_docsum 


OBJECTIVE: To investigate whether real or sham low-level laser therapy (LLLT) plus microamperes transcutaneous electric nerve stimulation (TENS) applied to acupuncture points significantly reduces pain in carpal tunnel syndrome (CTS).


 CONCLUSIONS:  This new, conservative treatment was effective in treating CTS pain; larger studies are recommended, with higher laser output energy levels. 


The Effects of Laser Therapy in Clinical Outcome and Neurophysiological Results of Carpal Tunnel...

The Effects of Laser Therapy in Clinical Outcome and Neurophysiological Results of Carpal Tunnel...

The Effects of Laser Therapy in Clinical Outcome and Neurophysiological Results of Carpal Tunnel...

http://www.ncbi.nlm.nih.gov/pubmed/18754533?ordinalpos=8&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum 


OBJECTIVE:  Carpal tunnel syndrome (CTS) is the most common neuropathy that can be diagnosed with confidence by the nerve conduction study (NCS). One of the recent treatments of CTS is the application of low power laser (LPL) therapy. The present study evaluates the effects of LPL irradiation through NCS and clinical signs and symptoms.


CONCLUSIONS:  Laser therapy as a new conservative treatment is effective in treating CTS paresthesia and numbness and improves the subjects' power of hand grip and electrophysiological parameters.  

Photobiomodulation of Pain in Carpal Tunnel Syndrome: Review of Seven Laser Therapy Studies

The Effects of Laser Therapy in Clinical Outcome and Neurophysiological Results of Carpal Tunnel...

The Effects of Laser Therapy in Clinical Outcome and Neurophysiological Results of Carpal Tunnel...

http://www.ncbi.nlm.nih.gov/pubmed/16706688?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&linkpos=5&log$=relatedreviews&logdbfrom=pubmed 


OBJECTIVE: In this review, seven studies using photo-radiation to treat carpal tunnel syndrome (CTS) are discussed: two controlled studies that observed real laser to have a better effect than sham laser, to treat CTS.


CONCLUSIONS:  Photo-radiation is a promising new, conservative treatment for mild/moderate CTS cases (motor latency < 7 m-sec; needle EMG, normal). It is cost-effective compared to current treatments.  

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Efficacy of Different Therapy Regimes of Laser in Painful Osteoarthritis of the Knee

The Effect of Laser in Knee Osteoarthritis: a Double-Blind, Randomized, Placebo-Controlled Trial

The Effect of Laser in Knee Osteoarthritis: a Double-Blind, Randomized, Placebo-Controlled Trial

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=OBJECTIVE&list_uids=14677160&query_hl=18&itool=pubmed_DocSum 


OBJECTIVE: A prospective, double-blind, randomized, and controlled trial was conducted in patients with knee osteoarthritis (OA) to evaluate the efficacy of infrared low-power Gallium-Arsenide (Ga-As) laser therapy (LPLT) and compared two different laser therapy regimes.  


CONCLUSIONS:  Our study demonstrated that applications of LPLT in different dose and duration have not affected results and both therapy regimes were a safe and effective method in treatment of knee OA; however, more studies are recommended, with higher laser output energy levels.  

The Effect of Laser in Knee Osteoarthritis: a Double-Blind, Randomized, Placebo-Controlled Trial

The Effect of Laser in Knee Osteoarthritis: a Double-Blind, Randomized, Placebo-Controlled Trial

The Effect of Laser in Knee Osteoarthritis: a Double-Blind, Randomized, Placebo-Controlled Trial

http://www.ncbi.nlm.nih.gov/pubmed/19530911?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=145 


OBJECTIVE: To assess the effectiveness of LLLT in the treatment of OA 


CONCLUSION:  Our results show that LASER THERAPY reduces pain in KOA and improves microcirculation in the irradiated area.  

Low level laser Therapy (Classes I, II and III) for Treating Osteoarthritis

The Effect of Laser in Knee Osteoarthritis: a Double-Blind, Randomized, Placebo-Controlled Trial

Laser Therapy is an Important Tool to Treat Disorders of the Maxillofacial Region

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=OBJECTIVE&list_uids=15266461&query_hl=62&itool=pubmed_DocSum 


OBJECTIVE: To assess the effectiveness of Laser Therapy in the treatment of osteoarthritis 


CONCLUSIONS:  For OA, the results are conflicting in different studies and may depend on the method of application and other features of the LASER THERAPY application. Clinicians and researchers should consistently report the characteristics of the LASER THERAPY device and the application techniques used. New trials on LASER THERAPY should make use of standardized, validated outcomes. Despite some positive findings, this meta-analysis lacked data on how LASER THERAPY effectiveness is affected by four important factors: wavelength, treatment duration of LASER THERAPY, dosage and site of application over nerves instead of joints. There is clearly a need to investigate the effects of these factors on LASER THERAPY effectiveness for OA in randomized controlled clinical trials.  (NOTE: This study, along with so many others, illustrates the need for researchers to use appropriate power (dose) levels according to tissue variability factors - Paul S.)

Laser Therapy is an Important Tool to Treat Disorders of the Maxillofacial Region

Effectiveness of Laser Therapy in Temporomandibular Joint Disorders: a Placebo-Controlled Study

Laser Therapy is an Important Tool to Treat Disorders of the Maxillofacial Region

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=OBJECTIVEPlus&list_uids=9796491&query_hl=1&itool=pubmed_docsum 


OBJECTIVE: The authors report on the effects of low-level laser therapy (LLLT) in the treatment of maxillofacial disorders.


CONCLUSIONS:  These results confirm that LASER THERAPY is an effective tool and is beneficial for the treatment of many disorders of the maxillofacial region.  


Effectiveness of Laser Therapy in Temporomandibular Disorder

Effectiveness of Laser Therapy in Temporomandibular Joint Disorders: a Placebo-Controlled Study

Effectiveness of Laser Therapy in Temporomandibular Joint Disorders: a Placebo-Controlled Study

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=OBJECTIVE&list_uids=12737331&query_hl=18&itool=pubmed_DocSum 


OBJECTIVE: To investigate the effectiveness of low-level laser therapy in the treatment of temporomandibular disorder and to compare treatment effects in myogenic and atherogenic cases. 


CONCLUSION:  Low-level laser therapy can be considered as an alternative physical modality in the management of temporomandibular disorder.  

Effectiveness of Laser Therapy in Temporomandibular Joint Disorders: a Placebo-Controlled Study

Effectiveness of Laser Therapy in Temporomandibular Joint Disorders: a Placebo-Controlled Study

Effectiveness of Laser Therapy in Temporomandibular Joint Disorders: a Placebo-Controlled Study

http://www.ncbi.nlm.nih.gov/pubmed/17803388?ordinalpos=164&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


OBJECTIVE: Laser Therapy treatment for pain caused by temporomandibular joint disorders (TMD) was investigated in a controlled study comparing applied energy density, subgroups of TMD, and duration of disorders.  


CONCLUSION:  The results suggest that LASER THERAPY (application of 10 J/cm(2) and 15 J/cm(2)) can be considered as a useful method for the treatment of TMD-related pain, especially long lasting pain.  



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